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When you look at March Madness gambling odds for the Sweet Sixteen at the sports book there are a couple of tips to think about. The #1 seeds have done pretty well in this round and you might only want to pick all 3 of them to advance to the weekend. Let’s check out some other things to think about as you handicap March Madness odds for Thursday and Friday’s games.




Leading Seed Matchups
#1 Kansas encounters #12 Richmond on Friday and if history is any indication this game should be a beat. #1 seeds have confronted #12 seeds a total of 17 times in NCAA Tournament history and they’ve won every single time with an average margin of win of 14.8 points per game. #1 Ohio State encounters #4 Kentucky and there have been plenty of these fights in tournament history where #1 takes on #4. The top seed has won 73% of the time however the average margin of win in March Madness odds is only 6.8 points per game. The other #1 seed outstanding is Duke and they take on #5 Arizona. This competition in the last has been all about the #1 seed as they have won 28 times and lost only six times. Their average margin of win is 7.4 points per game. It should be noted though that 3 of the last 4 #1 seeds to lose in this competition were Duke in 2000, 2002 and in 2005.

#2 Seeds
There are 3 figures two seeds outstanding as North Carolina performs Marquette, Florida encounters BYU whilst San Diego State performs Temple. North Carolina encounters Marquette who is a #11 seed and in history this competition has gone all the way up of the #2 seed as they have won 8 of 9 fights in history with an average margin of win of 6.7 points per game. The other two games are #2 against #3 seeds. The #2 seeds have won 21 of the 33 all-time games however the average margin of win is only 2.3 points per game.

VCU against. FSU and Butler against. Wisconsin
Virginia Commonwealth is a #11 seed whilst Florida State is a #10 seed and amazingly there has never been an 11v10 competition in the NCAA Competition. Butler is an 8 seed whilst Wisconsin is a 4 seed and there have been 5 earlier fights in March Madness gambling between an 8 and a 4 in NCAA history with the 8 seeds in fact winning 3 of the 5 fights.


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